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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 1
2000 2
2001 4
2002 3
2003 4
2004 4
2005 4
2006 6
2007 6
2008 3
2009 3
2010 12
2011 8
2012 13
2013 15
2014 9
2015 15
2016 9
2017 17
2018 11
2019 9
2020 11
2021 11
2022 7
2023 9
2024 0

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177 results

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Page 1
Friend or foe: ABCG2, ABCC1 and ABCB1 expression in triple-negative breast cancer.
Nedeljković M, Tanić N, Prvanović M, Milovanović Z, Tanić N. Nedeljković M, et al. Breast Cancer. 2021 May;28(3):727-736. doi: 10.1007/s12282-020-01210-z. Epub 2021 Jan 8. Breast Cancer. 2021. PMID: 33420675
We aimed to investigate the level and frequency of expression of the three most important ABC transporter, ABCG2, ABCC1, and ABCB1, according to breast cancer subtype. METHODS: We evaluated ABCG2, ABCC1, and ABCB1 protein expressions in 124 primary breast tumors (78 …
We aimed to investigate the level and frequency of expression of the three most important ABC transporter, ABCG2, ABCC1, and ABCB1, a …
Expression levels of ABCG2 and CD61 genes in breast cancer tissues of Iranian population.
Liaghati P, Momeni P, Oskooei VK, Ghafouri-Fard S, Taheri M. Liaghati P, et al. Breast Dis. 2020;39(3-4):137-142. doi: 10.3233/BD-200448. Breast Dis. 2020. PMID: 32894234
Among these genes are the stem cell markers CD61 and breast cancer resistance protein (BCRP or ATP-binding cassette super-family G member 2 (ABCG2)). ABCG2 is one of the major efflux transporters implicated in multidrug resistance in cancer cells. ...There was no si …
Among these genes are the stem cell markers CD61 and breast cancer resistance protein (BCRP or ATP-binding cassette super-family G member 2 …
Clinical relevance of CERK and SPHK1 in breast cancer and their association with metastasis and drug resistance.
Bhadwal P, Randhawa V, Vaiphei K, Dahiya D, Agnihotri N. Bhadwal P, et al. Sci Rep. 2022 Oct 29;12(1):18239. doi: 10.1038/s41598-022-20976-0. Sci Rep. 2022. PMID: 36309544 Free PMC article.
Computational network analysis revealed the association of CERK and SPHK1 with known metastasis markers MMP-2 and MMP-9 and drug resistance markers ABCC1 and ABCG2. Correlation analysis confirmed the associations of target genes with these markers in both local as well as …
Computational network analysis revealed the association of CERK and SPHK1 with known metastasis markers MMP-2 and MMP-9 and drug resistance …
Enhancing Chemosensitivity of Breast Cancer Stem Cells by Downregulating SOX2 and ABCG2 Using Wedelolactone-encapsulated Nanoparticles.
Das S, Mukherjee P, Chatterjee R, Jamal Z, Chatterji U. Das S, et al. Mol Cancer Ther. 2019 Mar;18(3):680-692. doi: 10.1158/1535-7163.MCT-18-0409. Epub 2018 Dec 26. Mol Cancer Ther. 2019. PMID: 30587555
Enhanced drug retention was achieved by downregulation of SOX2 and ABCG2, both of which contribute to drug resistance of the CSCs. In addition, nWdl prevented epithelial-to-mesenchymal transition, suppressed cell migration and invasion, and reduced the percentage of breast …
Enhanced drug retention was achieved by downregulation of SOX2 and ABCG2, both of which contribute to drug resistance of the CSCs. In …
Breast Cancer Resistance Protein: A Potential Therapeutic Target for Cancer.
Mehendale-Munj S, Sawant S. Mehendale-Munj S, et al. Curr Drug Targets. 2021;22(4):420-428. doi: 10.2174/1389450121999201125200132. Curr Drug Targets. 2021. PMID: 33243119 Review.
It is a half-transporter affiliated to the ATP- binding cassette (ABC) superfamily of transporters, encoded by the gene ABCG2 and functions in response to adenosine triphosphate (ATP). ...
It is a half-transporter affiliated to the ATP- binding cassette (ABC) superfamily of transporters, encoded by the gene ABCG2 and fun …
Tamoxifen resistance induction results in the upregulation of ABCG2 expression and mitoxantrone resistance in MCF-7 breast cancer cells.
Ghalehno AD, Abdi H, Boustan A, Jamialahmadi K, Mosaffa F. Ghalehno AD, et al. Naunyn Schmiedebergs Arch Pharmacol. 2023 Dec;396(12):3723-3732. doi: 10.1007/s00210-023-02567-6. Epub 2023 Jun 13. Naunyn Schmiedebergs Arch Pharmacol. 2023. PMID: 37310508
We also evaluated if the resistance to TAM leads to the cross-resistance toward mitoxantrone (MX), a well-known substrate of the ABCG2 pump. The ABCG2 mRNA and protein expression were compared in MCF-7 and its TAM-resistant derivative MCF-7/TAMR cells using RT-qPCR …
We also evaluated if the resistance to TAM leads to the cross-resistance toward mitoxantrone (MX), a well-known substrate of the ABCG2 …
Dihydrotestosterone Induces Chemo-Resistance of Triple-Negative Breast MDA-MB-231 Cancer Cells Towards Doxorubicin Independent of ABCG2 and miR-328-3p.
Al-Momany B, Hammad H, Ahram M. Al-Momany B, et al. Curr Mol Pharmacol. 2021;14(5):860-870. doi: 10.2174/1874467214666210531170355. Curr Mol Pharmacol. 2021. PMID: 34061013
RESULTS: Contrary to our hypothesis, treating MDA-MB-231 cells with DHT no effect towards tamoxifen or mitoxantrone, increased cell resistance towards doxorubicin was noted, concomitant with decreased expression of ABCG2. This under-expression of ABCG2 was also foun …
RESULTS: Contrary to our hypothesis, treating MDA-MB-231 cells with DHT no effect towards tamoxifen or mitoxantrone, increased cell resistan …
A meta-analysis and experimental data for multidrug resistance genes in breast cancer.
Zaib S, Tahir S, Masood N, Hameed A, Azra Y. Zaib S, et al. Afr Health Sci. 2022 Dec;22(4):1-9. doi: 10.4314/ahs.v22i4.2. Afr Health Sci. 2022. PMID: 37092084 Free PMC article.
OBJECTIVE: This is a two parts study; a meta-analysis exploring association of drug resistance (mdr1 and ABCG2) genes with breast cancer and mutational association with molecular subtypes of cancer. ...RESULTS: C3435T polymorphism of mdr1 gene was most commonly studied mut …
OBJECTIVE: This is a two parts study; a meta-analysis exploring association of drug resistance (mdr1 and ABCG2) genes with breast can …
GPER mediates decreased chemosensitivity via regulation of ABCG2 expression and localization in tamoxifen-resistant breast cancer cells.
Yu T, Cheng H, Ding Z, Wang Z, Zhou L, Zhao P, Tan S, Xu X, Huang X, Liu M, Peng M, Qiu YA. Yu T, et al. Mol Cell Endocrinol. 2020 Apr 15;506:110762. doi: 10.1016/j.mce.2020.110762. Epub 2020 Feb 19. Mol Cell Endocrinol. 2020. PMID: 32087276
Here, we are the first to show that the expression levels of GPER and ABCG2 are markedly increased in tamoxifen-resistant ER + metastases compared to the corresponding primary tumors. A plasma membrane expression pattern of GPER and ABCG2 was observed in patients wi …
Here, we are the first to show that the expression levels of GPER and ABCG2 are markedly increased in tamoxifen-resistant ER + metast …
Effects of ABCB1 and ABCG2 Polymorphisms on the Pharmacokinetics of Abemaciclib Metabolites (M2, M20, M18).
Maeda A, Ando H, Irie K, Hashimoto N, Morishige JI, Fukushima S, Ebi H, Uchida K, Iwata H, Sawaki M. Maeda A, et al. Anticancer Res. 2023 Mar;43(3):1283-1289. doi: 10.21873/anticanres.16275. Anticancer Res. 2023. PMID: 36854511
The purpose of the present study was to evaluate the effects of ABCB1 and ABCG2 polymorphisms on the pharmacokinetics of the abemaciclib metabolites M2, M20 and M18. ...No significant association was observed between abemaciclib metabolites and ABCB1 1236T>C, ABCB1 3435 …
The purpose of the present study was to evaluate the effects of ABCB1 and ABCG2 polymorphisms on the pharmacokinetics of the abemacic …
177 results